The new kid on the block, CGB for anxiety is grabbing attention for those wanting a non-pharmaceutical treatment.
No longer taboo, the conversation around cannabis is dramatically shifting. Cannabis is increasingly recognised as a complex botanical powerhouse, with its lesser-known compounds beginning to steal the spotlight.
One such compound is cannabigerol (CBG). Often overshadowed by its more famous siblings THC and CBD, CGB is equally worthy of attention, especially when it comes to managing anxiety.
The Mother of All Cannabinoids
One of over 100 cannabinoids found in cannabis, CBG, is often referred to as the ‘mother cannabinoid’. It stands out in the cannabis family tree. It is a non-euphoric compound, which means it doesn’t produce the high associated with THC. In the young cannabis plant, CBG is initially present as cannabigerolic acid (CBGA). As the plant matures, CBGA naturally transforms into other cannabinoids like THC and CBD. Because of this, CBG is found in lower concentrations in most mature plants.
What sets CBG apart, and why is it generating buzz in the wellness and medical communities? Unlike THC, CBG does not have intoxicating effects, making it an attractive option for those seeking the therapeutic benefits of cannabis without the psychoactive side effects. Meanwhile, though CBD has been the go-to for non-intoxicating relief, CBG has a different chemical structure and works through unique pathways in the body, which might offer new therapeutic benefits that CBD does not.
CBG v’s THC and CBD
To understand the unique position of CBG among its peers, it’s important to grasp the basic differences:
THC (Tetrahydrocannabinol): Known for its psychoactive effects, THC is the component that makes users feel high.
It’s often used for pain relief, to reduce nausea, and to increase appetite but may increase anxiety in some individuals.
CBD (Cannabidiol): Non-psychoactive like CBG, CBD is famed for its anti-anxiety, anti-inflammatory, and pain-relieving properties, without the intoxicating effects of THC.
CBG (Cannabigerol): Also non-psychoactive, CBG is less researched than THC and CBD but is believed to potentially help with pain, inflammation, and anxiety, possibly offering mechanisms of action different from both THC and CBD.
CBG and Anxiety: What Does the Research Say?
Known for its value in reducing inflammation, easing neurological conditions, and reducing pain, CGB’s effect on anxiety is still to be well understood.
The research, while is nascent but promising. Studies suggest that CBG can interact with both the CB1 and CB2 cannabinoid receptors in the brain. These receptors are part of the endocannabinoid system, which helps regulate mood, pain sensation, appetite, and memory. The interaction of CBG with these receptors could influence changes in neurotransmitter release, reducing anxiety and stress responses.
A study published in 2022 (Calapai et al) found that CBG does cause have anti-anxiety effects. And in a patient survey published in 2021 (Russo et al), CGB was reported to have a positive effect on anxiety, insomnia, chronic pain, and depression.
Some research suggests that CBG could act as a buffer to the sometimes anxiety-inducing effects of THC by modulating its impact.
Moreover, CBG has been shown to potentially boost anandamide, an endogenous cannabinoid known as the ‘bliss molecule’, which is integral to increasing dopamine levels and regulating various functions, including mood and feelings of well-being. By enhancing anandamide levels, CBG could naturally aid in improving mood and reducing anxiety.
Practical Considerations
Despite the potential benefits, if you’re considering using CBG for anxiety, there are a few practical aspects to keep in mind.
1. Quality and Sourcing: As with any cannabis product, the quality, purity, and source are crucial. If you’re wanting to improve your health, source products that have been grown in clean soil or environments and processed properly. Look for products that provide third-party lab results to ensure you are getting a high-quality product free from contaminants. Avoid buying on price alone or funky labeling.
2. Dosage: Because research is still developing, there is no standard dosage for CBG for anxiety. It’s wise to start with a low dose and gradually increase it based on how your body responds.
3. Consultation with Healthcare Providers: Always consult with a healthcare provider, especially if you’re currently taking other medications, to avoid any potential interactions.
The Road Ahead
While CBG’s role in anxiety management looks hopeful, it is clear that more research is needed to fully understand its mechanisms, benefits, and potential side effects.
The exploration of cannabis and its components is a testament to the plant’s complex nature and potential to contribute to health and wellness. As we continue to decipher the myriad benefits of compounds like CBG, we move closer to a future where personalised medicine could include these once-overlooked substances. For those dealing with anxiety, this could mean more natural treatment options that are effective, safe, and tailored to their specific needs.
Be happy. Be healthy.
